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Table 2 57 cases of synovial sarcoma of the hand-wrist in the Pub-Med English literature (1983–2020): demographic, pathologic, clinical, and therapeutic features are reported for each case

From: Synovial sarcoma of the hand-wrist: a case report and review of the literature

Case # Author Sex Age Race Location Duration of symptoms before diagnosis (years) Maximum dimension (cm) Histologic subtype Metastases at diagnosis Treatment Follow-up period (years) Follow-up outcome Previous erroneous diagnosis
1 Kinsella [22] F 18 NS Hand palmar surface NS NS NS No S + RT 2.5 No recurrence –
2 Adeyemi-Doro [23] F 23 African Finger 0.25 NS NS No S 0.25 Lung metastases –
3 Louis [24]a M 8 NS Hand palmar surface NS NS NS No S 12 Multiple local recurrences Fibroma
4 O’Leary [27] F 24 NS Wrist NS NS Poorly differentiated No S + RT 1.2 Lung metastases –
5 Weiss [28]a M 75 NS Hand palmar surface NS 2.5 Monophasic No S NS Lung metastases Carpal tunnel
6 Fleegler [30]aa F 82 NS Hand palmar surface/wrist 2 6.5 NS No S 0.5 Lung metastases Carpal tunnel
7 Fleegler [30]a F 42 NS Hand, between metacarpals 2 5 NS No S 10 No recurrence Arthritis
8 Brien [31] NS 27 NS Hand dorsal surface NS < 5 NS No S + RT 3 Died of recurrence of disease –
9 Brien [31] NS 16 NS Hand palmar surface NS < 5 NS No S + CT 1.1 Died of recurrence of disease –
10 Brien [31] NS 19 NS Hand, between metacarpals NS < 5 NS No S + CT 1.25 No recurrence –
11 Brien [31] NS 24 NS Hand dorsal surface NS > 5 NS No S 5.4 No recurrence –
12 Brien [31] NS 63 NS Hand palmar surface NS < 5 NS No S + RT 2.5 No recurrence –
13 Brien [31] NS 28 NS Hand palmar surface NS > 5 NS No S 4 No recurrence –
14 Brien [31] NS 18 NS Finger NS < 5 NS No S + RT 4.9 Died of recurrence of disease –
15 Brien [31] NS 42 NS Wrist NS < 5 NS No S + RT 2.5 Died of recurrence of disease –
16 Nakajima [34] F 23 Asian Hand palmar surface 0.2 0.6 Poorly differentiated No S 2.3 No recurrence –
17 Chesser [35] M 16 NS Median nerve at the wrist 1 2 Biphasic No S + RT 1 No recurrence –
18 Harjai [36] M 6 NS Hand palmar surface 3 3 Biphasic No S + RT   LTF –
19 McPhee [37] M 70 NS Finger NS ≤ 5 NS No S 2.25 No recurrence –
20 McPhee [37] M 41 NS Wrist NS ≤ 5 NS No S + RT 2.6 No recurrence –
21 Wong [39] M 35 NS Hand between metacarpals A few months NS Monophasic No S + RT   LTF –
22 Wong [39] M 20 NS Hand palmar surface 0.5 NS NS No S + RT   LTF –
23 Egger [40] F 34 NS Hand, between metacarpals 0.6 6 Monophasic No S + CT + RT 1 Lung metastasis –
24 Imaizumi [41]a F 11 NS Wrist 10 4 Monophasic No CT + S 1.1 No recurrence Juvenile rheumatoid arthritis
25 Kawai [42] M 9 NS Hand palmar surface 0.25 3 NS No S + CT 4.1 No recurrence –
26 Kawai [42] F 11 NS Wrist 1 3 NS No S + CT 4.5 No recurrence –
27 Kawai [42] M 25 NS Hand palmar surface 1.3 4 NS No S + RT + CT 2.8 No recurrence –
28 Michal [8] M 8 NS Hand palmar surface NS 0.8 Monophasic No S 2 No recurrence –
29 Michal [8] M 20 NS Snuff box NS 0.8 Monophasic No S + RT 14.7 No recurrence –
30 Michal [8] F 20 NS Hand-wrist, NOS NS 0.9 Monophasic No S + RT 7.5 No recurrence –
31 Michal [8] F 23 NS Finger NS 0.7 Monophasic No S 12.8 No recurrence –
32 Michal, [8] M 24 NS Finger NS 0.6 Biphasic No S   LTF –
33 Michal [8] M 29 NS Hand dorsal surface NS 0.5 Monophasic No S + RT + CT 14.7 No recurrence –
34 Michal [8] F 29 NS Hand, NOS NS 0.6 Biphasic No S   LTF –
35 Michal [8] F 35 NS Hand palmar surface NS 0.8 Monophasic No S   LTF –
36 Michal [8] F 37 NS Hand, NOS NS 0.5 Biphasic No S   LTF –
37 Michal [8] F 40 NS Hand, between metacarpals NS 0.6 Monophasic No S 17 No recurrence –
38 Michal [8] M 49 NS Hand dorsal surface NS 0.9 Biphasic No S + RT 32.2 No recurrence –
39 Michal [8] F 49 NS Finger NS 0.7 Monophasic No S 16.3 No recurrence –
40 Michal [8] F 49 NS Finger NS 0.9 Biphasic No S   LTF –
41 Muramatsu [45] M 61 NS Finger NS NS NS No S 11.4 No recurrence –
42 Bar [48] M 37 NS Hand, NOS NS NS Monophasic No S + RT 11 Lung metastasis –
43 Bar [48] M 30 NS Hand, NOS NS NS NS No S + RT 16 Lung metastasis –
44 Gilleard [49] M 12 NS Wrist 1.5 5 Biphasic No S + RT 2 No recurrence –
45 Puhaindran [50] M 80 NS Hand, NOS NS 7.5 NS No S + RT 1.7 No recurrence –
46 Puhaindran [50] M 40 NS Hand, NOS NS 6.5 NS No S + RT 10 No recurrence –
47 Steinstraesser [6] M 31 Caucasian Wrist 0.25 2.5 Biphasic No S + RT 1 No recurrence –
48 Casal [13] F 63 Caucasian Hand palmar surface 3 10 Monophasic No S + RT + CT 11.5 Died of local recurrence of disease –
49 Muramatsu [52, 70] M 40 NS Wrist 0.66 3 Monophasic No CT + S + RT 0.5 No recurrence –
50 Kim [53] M 26 NS Digital nerve NS 1.5 Monophasic No S + RT 1.5 No recurrence –
51 Maia [54] M 34 NS Wrist 0.25 3 Poorly differentiated No S 0.9 Lung and lymph node metastases –
52 Puhaindran [55] F 12 NS Wrist NS NS NS No S + RT + CT 9 Second tumor (osteosarcoma) –
53 Damato [58] M 50 Caucasian Hand, NOS NS NS Monophasic No S + RT 1 Local recurrence and multiple lung metastases –
54 Sahoo [60]a F 22 NS Hand palmar surface 10 NS Biphasic No S 6 Multiple local recurrences treated with RT, CT and surgical amputation. LTF after 3 additional years. Abscess with hematoma
55 Fujibuchi [64] F 77 NS Wrist 0.08 NS NS No S 2 No recurrence –
56 Karki [65] F 45 Caucasian Hand palmar surface 0.66 3 Monophasic No S 1 No recurrence –
57 Ohan [66] M 34 NS Hand palmar surface A few years 4.7 Monophasic No S + RT + CT 3.5 No recurrence –
  1. F female, M male, NS not specified, NOS not otherwise specified, S surgery, RT radiotherapy, CT chemotherapy
  2. aCases for which the first diagnosis was mistakenly different than synovial sarcoma and the patients were initially treated for the erroneous condition. In these cases, the “duration of symptoms before diagnosis”—whenever present—includes the period of treatment for the erroneous diagnosis
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Journal of Medical Case Reports

ISSN: 1752-1947